Open Fruity Loops Studio and create a new project by clicking the "File" button on your project window and selecting "New."
Choose a tempo for your beat by clicking the "Tempo" box near the top of your project window and entering a number. For example, an average tempo is approximately 120 beats per minute, while you may use 140 to 160 for a fast tempo or 90 to 100 for a slow jam.
Drag percussion samples onto your sampler. Your sample can be found in the left column, indicated by the names of individual drums and melody types. Your sampler appears as a small rectangular window on the left side of your main project window. Drag the samples that you want to use directly onto the sampler window. For example, if you want to create a drum beat, you might drag a "Kick," "Hi Hat" and "Clap."
Create a percussion sequence. Beside each sample name on your sampler, you will see a series of small boxes. Each box represents a beat on the time signature. For example, if you click and highlight every fourth box on your "Kick Drum" sample, a kick drum will play every fourth beat. Beneath it, you might want to add a clap on every second beat, or another sample of your choosing.
Create a second layer of audio for your melody. Once you have your percussion sequence saved, create your second layer by clicking your "Pattern" box, indicated by the letters "PAT" (directly beside the "Tempo" box) and selecting "Pattern 2."
Right-click any unused sample on your sampler window, hover your mouse over "Insert" and select "FL Keys." A virtual music keyboard will appear on your screen. Click the "Playlist" button (directly beside the "Pattern" button) to see your multi-track view.
Click the boxes on the row marked "Pattern 1" to apply your sample to the multi-track editor. For example, if you want the pattern to span for 64 beats, drag your mouse over 64 boxes on the grid to shade them.
Click "Pattern 2" on your playlist window and record a melody to accompany your percussion. You can use the keys on your computer keyboard to generate notes (just follow the guide on the virtual keyboard appearing on your screen) or connect an external MIDI keyboard to your computer. Click "Record" to record your sequence. The "Record" button looks like a small circle near the upper-left corner of your project window.
Save your beat by clicking the "File" button and selecting "Save."