Prepare hot, soapy water in a small bowl. Set aside.
Unplug your Mackie mixer from its power source.
Remove any other connections running into or out of the machine, such as XLRs or amps.
Remove any caps and slider knobs you wish to clean. Grasp the cap or knob and pull upward, gently.
Soak caps and knobs in the bowl of hot, soapy water. Let the condition of the caps/knobs determine how long they should soak. For example, if your knobs have built up a lot of grime, let them soak longer.
Scrub caps and knobs with a toothbrush. Pay particular attention to the small ridges and crevices to get them clean.
Rinse caps and knobs thoroughly with clean water. Set aside on paper towels to air dry.
Brush off dust and debris from your mixer with the paint brush. According to Mackie.com, "the bristles will easily remove dust from between the pots."
Use compressed air to blow dust and debris out of the fader tracks and other smaller, hard-to-reach areas.
Ensure that the caps and knobs have dried completely. When they have, return each to its proper place on the mixing console.