Popović played Prince Boško and Lord Walter Fitzwalter in the 2001 film Knights of the Round Table.
From 2002 to 2003 he played the role of Dr. Vuja in the RTS series Budva na pjenu od mora. He played the role of Goran Vuković in the television series The Otpisani (2014–2016).
Popović is also a professor at the Faculty of Dramatic Arts in Belgrade. He became the president of SOKOJ, a Serbian film industry workers union, in 2013.