Movies:
* Scream 2 (1997) - Sidney Prescott
* Urban Legend (1998) - Natalie Simon
* Jawbreaker (1999) - Courtney Shayne
* The Specials (2000) - Jill
* The Guru (2002) - Samantha
* Van Wilder (2002) - Gwen Pearson
* The Clearing (2004) - Lisa
* The Last Supper (2006) - Maggie
* Gridiron Gang (2006) - Shannon
* The Third Nail (2007) - Amanda
* The Realest Real (2008) - Linda
* The Legend of Secret Pass (2010) - Sarah
* My Sister's Keeper (2009) - Anna Fitzgerald's (Abigail Breslin) teacher
* The Wedding Ringer (2015) - Mrs. Palmer
* A Dog's Purpose (2017) - Hannah
Television:
* Beverly Hills, 90210 (1994-1998) - Maryanne "Millie" Hamilton
* The Charm School (2000) - Herself
* Skin (2003) - Chloe
* Law & Order: Special Victims Unit (2003) - Nicole Walker
* Nip/Tuck (2004) - Lily
* CSI: Miami (2005) - Beth
* The O.C. (2005) - Gwen
* Entourage (2006) - Herself
* Dirt (2007) - Lisa
* CSI: Crime Scene Investigation (2008) - Ashley
* Ghost Whisperer (2008) - Laura
* The Ex List (2008) - Jill
* Three Rivers (2009) - Sarah
* My Generation (2010) - Jenna
* The Good Wife (2011) - Wendy Scott-Carr
* House of Lies (2011) - Monica
* Grey's Anatomy (2012) - Dr. Heather Brooks
* CSI: NY (2013) - Dr. Harper
* Baby Daddy (2013-2017) - Bonnie
* Lucifer (2016) - Charlotte Richards
* The Last Ship (2016-2018) - Dr. Rachel Scott
* Insatiable (2018) - Coralee Armstrong
* The Rookie (2020) - Samantha
* 9-1-1 (2021) - Catherine
* Law & Order: Special Victims Unit (2021) - Nicole Walker
This is not an exhaustive list, as she has also appeared in a variety of other projects, including TV movies, documentaries, and short films.
Rebecca Gayheart has a versatile career spanning over three decades, showcasing her talent in both drama and comedy.