Main Cast
* Keanu Reeves as Kai
* Hiroyuki Sanada as Oishi
* Tadanobu Asano as Lord Kira
* Rinko Kikuchi as Mika
* Jin Akanishi as Oishi's son
* Min Tanaka as Lord Asano
* Ko Shibasaki as Princess Takara
* Cary-Hiroyuki Tagawa as Lord Mori
Supporting Cast
* Rick Genest as The Silent One
* Togo Igawa as Muramasa
* Ryo Iwamatsu as Lord Kanō
* Shiori Kutsuna as Ayame
* Neil Maskell as John Manjiro
* Peter Stormare as The Dutch Trader
* Sean Briggs as The Assassin
This list includes the key roles in the film. You can find a more comprehensive cast list on websites like IMDb.