Parents:
* Brian Keith as John "Tom" Bradford
* Edna Garrett as Katherine "Kate" Bradford
Children:
* Kim Richards as Alice "Cissy" Bradford
* Mike Evans as Bill Bradford
* Danny Bonaduce as Danny Bradford
* Suzanne Somers as Chrissy Bradford
* Anissa Jones as Cindy Bradford
Grandparents:
* Richard Deacon as Walter "Grandpa" Bradford
* Margaret Hamilton as Alice "Grandma" Bradford (original cast member)
* Lillian Bronson as Alice "Grandma" Bradford (later cast member)
It's worth noting that the series went through some cast changes, with the original "Grandma" Margaret Hamilton leaving after the first season and being replaced by Lillian Bronson.
This cast made *The Patchwork Family* a popular TV show, and their performances resonated with audiences.