* Brenda Walsh in *Beverly Hills, 90210*: This role was her breakout and she played the character for four seasons, becoming a teen icon of the 90s.
* Prue Halliwell in *Charmed*: This role showcased her strength and dramatic talent as the oldest Halliwell sister, a powerful witch who protected the world from evil.
* Jill Munroe in *Charlie's Angels*: Doherty played the role in the 2000 film adaptation, alongside Cameron Diaz and Drew Barrymore.
* Other notable roles: She has appeared in films such as *Mallrats*, *She's All That*, and *Little House on the Prairie*. She also had a recurring role on *North Shore* and appeared in several TV movies.
Doherty's career has spanned decades, showcasing her versatility as an actress. She has also been open about her personal struggles, including her battle with breast cancer, which has made her a role model for many.