This classic British science fiction series featured a family of five brothers who piloted incredible rescue vehicles called "Thunderbirds" to help those in need around the world. The show used elaborate puppets and models to bring these vehicles and the brothers to life.
Other possible answers, depending on what you're remembering:
* "Space: 1999" (1975-1977) used puppets for some alien creatures and characters, though it wasn't the central focus like "Thunderbirds".
* "The Hitchhiker's Guide to the Galaxy" (2005) used puppets for the alien character Marvin the Paranoid Android.
Is there anything else you remember about the show, like the plot, characters, or other details? This might help narrow down the possibilities further.