However, they share a significant connection:
* They are both mutants with shapeshifting abilities. Mystique can perfectly mimic the appearance and voice of anyone, while Nightcrawler can teleport and has blue skin and a tail.
* Both characters are often associated with the X-Men, though their allegiances have fluctuated throughout the years.
* Their relationship has been complex and often antagonistic. Mystique has a history of being a villain, and she has manipulated and even attacked Nightcrawler on multiple occasions.
* Nightcrawler is, however, the son of Mystique's long-time friend and former lover, Azazel.
Therefore, Mystique and Nightcrawler are not blood relatives, but they share a complicated history through their shared mutant heritage, their association with the X-Men, and Nightcrawler's connection to Azazel.