Film:
* The Last of the Mohicans (1992): As Uncas, a character based on the real-life Mohican leader. This was his breakout role.
* The Twilight Zone (2019): He played the role of "The Traveler" in the episode "The Traveler".
* A Christmas Carol (2009): He played the role of "Ghost of Christmas Present" in this TV movie.
* The Revenant (2015): He played the role of "Arikara Chief".
* The Lone Ranger (2013): He played the role of "Chief Tonto".
* The Dead Don't Die (2019): He played the role of "Officer Miguel".
Television:
* The Secret Life of the American Teenager: Played the role of "Nick".
* The Strain: Played the role of "Gus".
* Black Summer: Played the role of "William".
* Reservation Dogs: Played the role of "Elora Danan" (voice).
* Rutherford Falls: Played the role of "Terry Thomas".
* Ghosts: Played the role of "Sam" in the TV series.
This is not an exhaustive list, but it represents some of Lorne Cardinal's most prominent and critically acclaimed work. He is a versatile actor who has demonstrated his ability to play a wide range of characters, from historical figures to modern-day heroes.