Here are some of the most prominent contenders:
Oprah Winfrey: Arguably the most influential talk show host of all time, Oprah built an empire through her honesty, empathy, and ability to connect with audiences on a personal level. Her show, *The Oprah Winfrey Show*, ran for 25 seasons and had a significant impact on pop culture and television.
Ellen DeGeneres: Known for her comedic timing, genuine personality, and advocacy for LGBTQ+ rights, Ellen DeGeneres hosted *The Ellen DeGeneres Show* for 19 seasons, becoming a beloved figure and creating a positive and uplifting atmosphere.
Phil Donahue: While technically not a woman, Phil Donahue revolutionized the talk show format with his focus on controversial and social issues. He paved the way for many female talk show hosts and was considered a groundbreaking figure in the genre.
Barbara Walters: A pioneer in television news and talk shows, Barbara Walters broke barriers by becoming the first woman to co-host a major network news program and later created her own successful talk show, *The View*.
Rosie O'Donnell: A controversial but influential figure, Rosie O'Donnell was known for her outspokenness and willingness to tackle tough topics. Her show, *The Rosie O'Donnell Show*, was a popular destination for celebrity interviews and social commentary.
Ultimately, the choice of "talk show queen" is up to you. Each of these women made significant contributions to the genre and left their mark on television history.