- Amos 'n' Andy: A comedy sketch show about two African American friends living in Chicago, played by white actors Freeman Gosden and Charles Correll.
- The Avalon Time: A pop and jazz variety show hosted by popular bandleader Vincent Lopez.
- The Fleischmann Hour: A variety show sponsored by the Fleischmann's Yeast company, featuring a mix of music, comedy, and sketches.
- The Literary Digest Hour: A news and current events program based on the popular weekly newsmagazine of the same name.
- The Magic Carpet: A children's show that used sound effects and music to create vivid imaginary worlds.
- The National Farm and Home Hour: A daily show providing agricultural news and information, hosted by USDA officials and farmers.
- The New York Philharmonic Symphony: Weekly live broadcasts of concerts by the New York Philharmonic Orchestra.
- The Original Amateur Hour: A talent show featuring amateur performers from across the country.
- The Palmolive Hour: A variety show sponsored by the Palmolive soap company, featuring live performances by popular singers, comedians, and orchestras.
- The Real Life Stories: A drama program presenting fictionalized accounts of real-life events and people.
- Rudy Vallee's Fleischmann Hour: A pop music variety show hosted by singer and bandleader Rudy Vallee, featuring guest stars and his own orchestra.
- The Saturday Night Jamboree: A live country music show featuring barn dance and square dancing, along with performances by popular country musicians of the day.
- The Sketch Book of Will Rogers: A comedy show featuring humorist and political commentator Will Rogers, providing satirical takes on current events.
- Uncle Don: A children's show hosted by "Uncle Don" Wilson, featuring stories, music, and educational content.