Place your mixer in a location that will allow you to hear the sound coming from the speakers clearly. The best placement is opposite the speakers, centered between the left and right pair. Connect the power supply to your mixer.
Connect the female end of an XLR cable to a microphone. Run the other end of the cable to your mixing board. Plug the male end into the "Mic" port of an open channel. These channels provide the preamps that will shape the sound characteristics of the microphone signal, processing them for output. Repeat the process for each microphone in your rig.
Connect one end of a balanced 1/4-inch cable to the left channel jack labeled "L" found on the "Main Out" panel. Connect another cable to the right channel jack with the "R" label. Connect the opposite end of each cable to the matching left and right inputs on you amplifier.
Power on your mixer and amplifier. Test each microphone connected to the mixer for output.
Adjust the volume of each microphone channel to create a balanced mix. Use the "EQ" knobs to shape the tone and cut out frequencies that are causing squeal and feedback.