* Aaron Dismuke as Edward Elric
* Vic Mignogna as Ling Yao
* Caitlin Glass as Winry Rockbell
* Christopher Sabat as Maes Hughes
* Colleen Clinkenbeard as Riza Hawkeye
* J. Michael Tatum as Roy Mustang
* Laura Bailey as Lust
* Michael Sinterniklaas as Greed
* Patrick Seitz as Father
* Stephanie Young as Olivier Mira Armstrong
* Travis Willingham as Alex Louis Armstrong
* Veronica Taylor as May Chang
Japanese
* Romi Paku as Edward Elric
* Jun Fukuyama as Ling Yao
* Megumi Toyoguchi as Winry Rockbell
* Unshō Ishizuka as Maes Hughes
* Michiko Neya as Riza Hawkeye
* Tōru Ōkawa as Roy Mustang
* Megumi Hayashibara as Lust
* Jun'ichi Suwabe as Greed
* Norio Wakamoto as Father
* Yōko Soumi as Olivier Mira Armstrong
* Kenyu Horiuchi as Alex Louis Armstrong
* Yui Horie as May Chang