- Jim Morrison (The Doors): Died in 1971 at the age of 27 from alcohol-related complications.
- Jimi Hendrix (The Jimi Hendrix Experience): Died in 1970 at the age of 27 from asphyxia caused by his own vomit after mixing alcohol and barbiturates.
- Janis Joplin (Big Brother and the Holding Company): Died in 1970 at the age of 27 from an overdose of heroin and alcohol.
- John Bonham (Led Zeppelin): Died in 1980 at the age of 32 from alcohol-related asphyxiation.
- Keith Whitley (Country music singer): Died in 1989 at the age of 33 from alcohol-related causes.
- Scott Weiland (Stone Temple Pilots, Velvet Revolver): Died in 2015 at the age of 48 from a mixture of drugs and alcohol.
- Lemmy Kilmister (Motörhead): Died in 2015 at the age of 70 from prostate cancer and substance abuse.
- George Michael (Solo career, Wham!): Died in 2016 at the age of 53 from a heart attack and fatty liver disease, which was caused by his drinking and drug use.