- Declining viewership: The show's viewership had been declining for several seasons, and by the time it was canceled, it was averaging only about 8 million viewers per episode. This was a significant decline from its peak of over 20 million viewers per episode in its early seasons.
- Creative differences: There were also creative differences between the show's producers and some of its stars, including David Caruso, who played Horatio Crane. These differences led to Caruso's departure from the show in 2012, which many believe was a major factor in the show's decline in popularity.
- Changing television landscape: The television landscape had changed significantly since CSI: Miami first aired in 2002. There was increasing competition from other scripted dramas, as well as from reality TV and streaming services. This made it more difficult for CSI: Miami to maintain a large and loyal audience.
- Desire to end on a high note: The producers of CSI: Miami wanted to end the series on a high note, rather than letting it decline further. They felt that the show had run its course and that it was time to bring it to a close.