- The Big Bang Theory (2016–present) as Dr. Leslie Winkle
- Raising Hope (2010–2014) as Jimmy Chance
- That's My Bush! (2001) as First Son George W. Bush
- The Simpsons (2000–present) as Richard (voice)
- Futurama (1999–2003, 2008) as Zapp Brannigan (voice)
- NewsRadio (1995–1999) as Jimmy James
Movies:
- The Lego Batman Movie (2017) as the Joker (voice)
- Ralph Breaks the Internet (2018) as Yesss (voice)
- Cloudy with a Chance of Meatballs 3 (2023) as Monkey (voice)
- The Powerpuff Girls Movie (2021) as Professor Utonium (voice)
- Despicable Me 3 (2017) as Balthazar Bratt (voice)
- Trolls (2016) as Branch (voice)
- Sausage Party (2016) as Frank the Hot Dog (voice)