1. CXCL16, also known as SR-PSOX: CXCL16 is a chemokine that is expressed in various cell types, such as endothelial cells, epithelial cells, and activated T cells. It acts as a ligand for the CXCR6 receptor and is involved in immune cell recruitment, angiogenesis, and tumorigenesis.
2. CX3CL1, also known as fractalkine: CX3CL1 is a unique chemokine that has a chemokine domain at the N-terminus and a mucin-like domain at the C-terminus. It is expressed on the surface of some immune cells, including monocytes and endothelial cells. CX3CL1 binds to the CX3CR1 receptor and plays a role in immune cell migration, adhesion, and activation.
3. CLEC2D, also known as DCIR2: CLEC2D is a C-type lectin receptor expressed on the surface of dendritic cells and macrophages. It recognizes certain pathogens and initiates immune responses by promoting phagocytosis and cytokine production.
These are just a few examples of Tango receptors, and their specific functions and roles in the immune system can vary depending on the receptor and the context in which they are expressed. The study of Tango receptors is an active area of research, and ongoing investigations aim to further elucidate their significance in health and disease.