The song is about a relationship that has ended, and the singer's longing for their former partner. The lyrics express the singer's feelings of loss and regret, and their desire to be reunited with their ex-lover. The song features a distinctive guitar riff and a driving rhythm section.
"I Miss You" was a commercial success, reaching number one on the Billboard Alternative Songs chart and number two on the Billboard Mainstream Rock chart in the United States. The song was also a top 10 hit in several other countries, including Australia, Canada, and the United Kingdom. The song has been certified triple platinum by the Recording Industry Association of America (RIAA).
The song was accompanied by a music video, directed by Mark McGrath and Richard Vidan. The video features the band performing the song in a variety of locations, including a bedroom, a park, and a beach. The video also features a number of cameos, including appearances by comedian Ben Stiller and actress Shannon Elizabeth.
"I Miss You" has been praised for its catchy melody and heartfelt lyrics. The song has been covered by a number of artists, including Fall Out Boy, All Time Low, and Avril Lavigne. "I Miss You" is considered one of Blink-182's most popular and enduring songs.