* The Wizard of Oz: While not the central plot element, the tornado that whisks Dorothy away to Oz is arguably one of the most iconic and recognizable tornado depictions in literature. It's the driving force behind the entire story, and the image of Dorothy's house flying through the air has become synonymous with tornadoes.
* The Grapes of Wrath: John Steinbeck's epic novel depicts the Dust Bowl era, which included devastating dust storms, often referred to as "black blizzards" that were as destructive as tornadoes. Though not a specific tornado event, these storms play a pivotal role in the story, symbolizing the hardship and displacement faced by the Joad family.
* "The Twister" by John Grisham: This thriller features a powerful tornado that devastates a small town, and the aftermath becomes entangled in a complex legal case involving insurance fraud and corruption. While not as iconic as some others, the book highlights the devastating impact of tornadoes and their social consequences.
* "The Storm" by Daniel Defoe: While not specifically about tornadoes, this novella depicts a powerful storm that batters London in 1703. It provides a vivid and realistic account of the storm's destruction, mirroring the effects of tornadoes.
Ultimately, the "most famous" tornado in literature is subjective and depends on your personal interpretation and familiarity with different works. However, the above examples highlight some of the most significant and enduring tornado depictions in literature.