Increased abolitionist sentiment: The powerful portrayal of enslaved individuals' struggles and abuse in the novel ignited outrage and increased support for the abolitionist movement. It brought the institution of slavery and its associated human suffering to life for many northern readers, who had not necessarily come into close contact with it in their own daily lives. Thousands who read the book joined abolitionist campaigns.
Influenced political figures: "Uncle Tom's Cabin" caught the attention of prominent U.S. senators such as Charles Sumner and William H. Seward. President Abraham Lincoln reportedly met Stowe and referred to her as "the little lady who made this big war."
International influence: The book gained immense popularity globally and was quickly translated into more than 30 languages. It generated an outcry against American slavery from countries worldwide. This international outrage added external pressure on the United States to address human rights and slavery within its boundaries.
Impact on the Civil War: Although there is no definitive direct line of causation, many historians speculate that "Uncle Tom's Cabin" helped shape public perception and contribute to the Northern war effort during the American Civil War, which aimed in part to end slavery.