While Gargamel is the main antagonist, he is not the only villain. Here are some others who have appeared in the Smurfs franchise:
* Azrael: Gargamel's loyal, but dimwitted cat who helps him in his schemes.
* Hortense: A rival witch who sometimes joins forces with Gargamel.
* Scruple: A villainous, greedy businessman who wants to exploit the Smurfs' inventions.
* The Grouches: A group of grumpy and lazy creatures who constantly cause trouble for the Smurfs.
Though there are various villains, Gargamel is the most prominent and recurring bad guy in the Smurfs franchise.