Determine what type of comic you want to draw --- a simple, three-panel joke or a more contemplative twelve-panel comment on society. Decide on the number of characters, the content of the dialogue and the approximate number of panels. A good storyline is crucial to any good comic.
Sketch out by hand the general structure of the comic. If you have never drawn comics before, you may want to start with the classic three-panel comic. Decide which characters will be in each scene and leave enough room for their speech bubbles.
Use the rectangular tool to draw three rectangles on the screen. Make sure that the panels have the same dimensions, as the sizes of the panels should not be a distraction from the main point of your comic. You can copy and paste (Ctrl + C, then Ctrl + V) the first rectangle multiple times.
Draw the bodies of your characters with the shape tools available in Paint. Use the circle tool for the head, the line tools for the body and limbs and the brush tools to mark the facial features. One way to make your stick figures look more professional is to customize your character's heads. Make the shapes slightly more oval or more flattened, and keep that shape consistent in later panels. Also, choose a specific way in which you draw hands and feet.
For more realistic characters, use different combinations of the shape tools. Circles are good for drawing heads, eyes, buttons and certain mouth expressions. The line tool can outline arms, legs, torsos, most clothing and certain hairstyles. The curve is good for noses, simple smiles, eyebrows, ornate decorations on clothes, shoes and ears.
Use the text tool to write out the speech of each character. Choose a font that works well with your comic and fits in with the theme of your jokes. Avoid using generic Sans Serif or Script fonts on Word. Instead, look for lesser known fonts on the Web. For more serious comics, you can try using fonts with straighter lines and more angles, and for more humorous comics you can try a more bubbly, slanted font. This will not only give your comic a more authentic feel but contribute to your message. Once your words have been laid out, create the speech bubbles by first constructing an oval around the words with the circle tool. Use the line tool to draw in the lines that connect your bubbles to the speakers.
Add color to your comic, if desired. Color is not always necessary, but it can make your comic very rich if used wisely. Fill in any enclosed place with the "Fill with Color" icon, which looks like a dripping paint bucket. Click on this icon, choose the color you want to fill with, and click on the space, such as a shirt, that you want to be colored.
Look over your comic once again and see if you missed any details. If lines go outside of their borders or words go through speech bubbles, get rid of the excess with the eraser tool. Finish your comic by signing your name. Use the text tool to place your signature either on the bottom right or in the gutter, the space between the panels.