Purchase a spiral binding machine or find someone who'll let you use theirs.
Make sure that the machine is set to the right margins and that any other necessary settings are in place.
Gather the materials that need spiral binding. Double check that all pages, including the front and back covers, are there (and in the correct order!) before binding the document.
Using the paper hold punch on the spiral binding machine, punch holes in the papers of your document, a few pages at a time. Make sure that the number of pages you punch each time doesn't exceed the maximum thickness allowed by your spiral binding machine.
Use the instructions for your specific machine to actually apply the spiral binding. Be sure to leave about 1/4" of the spiral binding extending from both ends of the document.
Use the coil crimping pliers to get rid of the excess coil. Be sure there are no sharp edges of spiral binding sticking out; if there are, use the pliers to bend them in toward the document.