People:
* Reginald Dwight, better known as Elton John, a legendary English singer, songwriter, and composer.
* Reba McEntire, an American singer, actress, and television personality.
* Reese Witherspoon, an Academy Award-winning American actress.
* Richard Gere, a renowned American actor.
* Robert Englund, an American actor known for his role as Freddy Krueger in the *Nightmare on Elm Street* franchise.
* Ron English, a renowned American artist known for his pop art style.
* Renee Zellweger, an Academy Award-winning American actress.
* Rupert Everett, a British actor and screenwriter.
Characters:
* Red Riding Hood, a classic fairytale character.
* Remy (from *Ratatouille*), a charming rat with a passion for cooking.
* R2-D2, a beloved droid from the *Star Wars* franchise.
* Regina George (from *Mean Girls*), a popular and somewhat mean high school student.
* Rick Grimes (from *The Walking Dead*), a sheriff's deputy who becomes a leader in a post-apocalyptic world.
This is just a small selection, and there are many other famous people and characters with the initials RE.
Let me know if you'd like me to focus on a specific area, like actors, musicians, or fictional characters!