Consider the atmosphere that you want to set with your sound and light show. If you want something dark and mysterious, choose darker colors with low hues such as black, purple, dark, red, and blew.
Consider what sorts of sounds you want to accompany the show. The auditory experience you want to create should be congruent with the ambiance that created by the lights. If the lighting and audio clash, the show could be hard to understand and may give off conflicting messages.
Set up the lights in the locations where you feel they would be most effective. Be sure to consider factors such as the audience's view, as you do want want the lights to obstruct their vision.
Set up the speakers for your sound and light show. Consider the location of the audience when you place the speakers. Direct the sound towards them, but not so close that it will interrupt their hearing and detract from the show's experience.