- Robin Williams - Seymour Parrish
- Dustin Hoffman - Walter Finch
- Connie Nielsen - Erica Olsen
- Carla Gugino - Lydia
- John Turturro - Seymour "Sy" Parrish, Jr.
- Michael Peña - Juan
- Laura Elena Harring - Nina Romano
- Amy Aquino - Enfermera
- Marianne Leone Cooper - Sra. Parrish
- Marc Margolis - Don
- Miltos Yerolemou - Detective Garcia
- Christopher J. Hanke - Detective
- George Touliatos - Detective
- George Wyner - Hombre de los hotdogs