* Ethan Hawke as David
* Samantha Harris as Sarah
* Allie Rowka-Alin as Alice
* Justin Bartha as Mike
* Caleb Emerson as Michael
* Rebecca Henderson as Emily
* John Benjamin Hickey as Michael's dad
* Marylouise Burke as Michael's mom
* Stephen McKinley Henderson as Dr. Hayes
* John Rothman as Dr. Rosen
* Aasif Mandvi as Dr. Desai
* John Cenatiempo as David's Therapist
* Anthony Rapp as Mark
* Sarah Paulson as Lucy
It's worth noting that the film was a very personal project for Ethan Hawke who also co-wrote the script.