* Javier Bardem as Casal
* Edward James Olmos as Sepúlveda
* Sergi López as Jean de la Casa
* Pierre Vaneck as Cardinal
* Jean-Pierre Cassel as Philip II
* Fernando Rey as The Doctor (final film appearance before his death)
* Manuel Alexandre as Don Juan
* Luis Escobar as Prior
* Ana Torrent as Inés de la Cruz
It's worth noting that this is a very international cast with actors from Spain, Mexico, France, and Argentina.