* Liev Schreiber as Damien Thorn
* Faye Dunaway as Katherine Thorn
* Mía Farrow as Nancy, a journalist who is investigating Damien
* Donal Logue as Father Brennan, a priest who helps Nancy
* Seaman as Damien as a child
* Ruben Blades as Bugenhagen, a demonologist
* David Dukes as Senator Baylock, a powerful and sinister man
The film was directed by John Moore and was a remake of the original 1976 film "The Omen."