* John Schneider as Bo Duke
* Tom Wopat as Luke Duke
* Catherine Bach as Daisy Duke
* James Best as Sheriff Rosco P. Coltrane
* Sorrell Booke as Boss Hogg
* Denver Pyle as Uncle Jesse Duke
* Bing Crosby as Ben Duke
Recurring cast
* Sonny Shroyer as Deputy Enos Strate
* Rick Hurst as Deputy Cletus Hogg
* Nedra Volz as Lulu Hogg
* Waylon Jennings as The Balladeer