- The Running Man (1987): the band's song "Catholic School Girls Rule" is featured in the film.
- Less than Zero (1987): the band's song "Taste the Pain" is featured in the film.
- Tough Guys Don't Dance (1987): the band's song "Fire" is featured in the film.
- The Malibu Bikini Shop (1989): the band's song "Higher Ground" is featured in the film.
- Point Break (1991): the band's song "Give It Away" is featured in the film.
- Coneheads (1993): the band's song "Soul to Squeeze" is featured in the film.
- Wayne's World (1992): the band appears as themselves in the film, performing the song "Under the Bridge."
- Beavis and Butt-Head Do America (1996): the band's song "Love Rollercoaster" is featured in the film.
- The Simpsons (1991): the band appears in the episode "Krusty Gets Cancelled" as themselves, performing the song "Give It Away."
- Californication (2007-2014): the band's song "Otherside" is featured in the series finale.
- Breaking Bad (2008-2013): the band's song "Breaking Bad Theme" is the opening theme of the series.
In addition to these projects, Red Hot Chili Peppers have also contributed music to video games, commercials, and other media.