The sulpha triad drugs work by inhibiting the synthesis of folic acid, which is a vitamin that is essential for the growth and reproduction of bacteria. By blocking the synthesis of folic acid, these drugs prevent bacteria from multiplying and spreading.
The sulpha triad drugs were very effective in treating a wide range of bacterial infections, including pneumonia, meningitis, gonorrhea, and syphilis. However, they were also associated with a number of side effects, including nausea, vomiting, diarrhea, and skin rashes. In some cases, the sulpha triad drugs could also cause serious liver damage and kidney failure.
Due to the side effects, the sulpha triad drugs were eventually replaced by newer and safer antibiotics. However, these drugs played a major role in the development of modern chemotherapy, and they saved millions of lives.