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What is the difference between conjugation and hyperconjugation?

Both conjugation and hyperconjugation involve the interaction of electrons to stabilize a molecule, but they differ in the orbitals involved and the mechanism of interaction.

Conjugation:

* Involves: Overlap of p-orbitals in a system of alternating single and double bonds (or other pi systems).

* Mechanism: The p-orbitals align and overlap, forming a delocalized pi-electron system. This delocalization spreads the electron density over a larger area, increasing stability.

* Examples: Alkenes, alkynes, aromatic compounds, conjugated ketones.

* Effects:

* Increased stability: The delocalization of electrons lowers the energy of the system.

* Changes in chemical reactivity: Conjugation can alter the reactivity of functional groups.

* UV-Vis spectroscopy: Conjugated systems often absorb UV-Vis light due to the delocalized electrons.

Hyperconjugation:

* Involves: Overlap of the sigma bond (C-H or C-C) with an adjacent empty or partially filled p-orbital.

* Mechanism: The electrons in the sigma bond are "donated" to the empty or partially filled p-orbital, leading to a delocalization of electron density.

* Examples: Alkanes, carbocations, free radicals.

* Effects:

* Increased stability: Hyperconjugation stabilizes carbocations and radicals by dispersing the positive charge or unpaired electron.

* Alkanes: Hyperconjugation contributes to the stability of alkanes, even though they are not directly conjugated.

* NMR spectroscopy: Hyperconjugation can influence the chemical shift of protons in NMR spectra.

Here's a table summarizing the differences:

| Feature | Conjugation | Hyperconjugation |

|---|---|---|

| Orbitals involved | p-orbitals | sigma bonds and p-orbitals |

| Mechanism | Overlap of p-orbitals | Overlap of sigma bonds with p-orbitals |

| Examples | Alkenes, alkynes, aromatic compounds | Alkanes, carbocations, radicals |

| Stability | Increased stability due to delocalization | Increased stability by dispersing charge or unpaired electrons |

In short:

* Conjugation: Delocalization of pi electrons in p-orbitals.

* Hyperconjugation: Delocalization of sigma electrons into adjacent p-orbitals.

Both conjugation and hyperconjugation are important for understanding the structure, reactivity, and spectroscopic properties of molecules.

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