* Dominic Purcell as Lincoln Burrows
* Robin Tunney as Veronica Donovan
* Amaury Nolasco as Fernando Sucre
* Wade Williams as Brad Bellick
* Robert Knepper as Theodore "T-Bag" Bagwell
* Peter Stormare as John Abruzzi
* Jodi Lyn O'Keefe as Gretchen Morgan