Who are the two people who largely responsible for Romeo and Juliets death?

The two people who are largely responsible for Romeo and Juliet's death are Friar Laurence and the Nurse. Friar Laurence is the one who suggests that Romeo and Juliet fake their deaths in order to be together. This plan is ultimately unsuccessful and leads to their actual deaths. The Nurse is the one who gives Juliet the potion that makes her appear dead. This potion is what leads Romeo to believe that Juliet is dead and cause him to kill himself.