Television:
* Supernatural (2005-2020): This is arguably his most famous role, playing the angel Castiel in the long-running fantasy drama. He appeared in a recurring capacity starting in Season 4 and eventually became a main character.
* The West Wing (2004): This political drama series featured Collins in a one-episode role as "Marty."
* 24 (2006): He appeared in two episodes of this action thriller series as "Jimmy"
* The O.C. (2007): Collins had a recurring role in this teen drama as "Jim," the roommate of Ryan Atwood's best friend.
* Ringer (2011-2012): He had a recurring role in this thriller series playing "Agent Andrew Parker."
* The Tomorrow People (2013-2014): He guest-starred in two episodes of this sci-fi series.
* Girl Meets World (2016): Collins guest-starred as a "History Teacher" in this Disney Channel series.
* The Flash (2016): He appeared as "The Trickster" in this superhero drama.
* The 100 (2017): Collins had a guest appearance in this post-apocalyptic series.
* The Boys (2019-2023): Collins appeared as "The Legend" in this superhero satire series.
* The Winchesters (2022-present): Collins serves as a narrator in this prequel to "Supernatural," and he has also directed a few episodes.
Movies:
* The American Astronaut (2001): This science fiction film was Collins' debut, playing "Pilot."
* The Plight of Clownana (2003): Collins starred as "The Clown."
* The Best Laid Plans (2009): This comedy film featured Collins in the role of "Jeff."
* The Possession (2012): Collins played the role of "Clyde" in this horror film.
* The Girl on the Train (2016): He played "Tom" in this psychological thriller based on the novel.
* The Adventures of Ducky & Boots (2019): Collins voiced the character of "Boots" in this animated film.
Other:
* "Supernatural" Conventions: Collins frequently participates in fan conventions for "Supernatural," where he interacts with fans and participates in panels.
* "GISHWHES": Collins is the creator of "GISHWHES" (Greatest International Scavenger Hunt the World Has Ever Seen), an annual online scavenger hunt.
This list is not exhaustive, but it covers some of the most prominent projects Misha Collins has been involved in. He has a diverse range of work across various genres, including action, drama, comedy, horror, and even animation.