* Dean is severely injured by a werewolf.
* Season 2, Episode 1: "In My Time of Dying"
* Dean is stabbed in the heart by Alastair, an angel of Hell.
* Season 2, Episode 3: "Bloodlust"
* Dean is scratched by a shapeshifter, turning him into a werewolf.
* Season 4, Episode 3: "In the Beginning"
* Dean is thrown around a room like a doll by demons
* Season 6, Episode 20: "The Man Who Knew Too Much"
* Dean is shot in the shoulder by Dick Roman, a leviathan.
* Season 12, Episode 23: "All in the Family"
* Dean is impaled by the Prince of Hell, Asmodeus