* Thomas Ian Nicholas as Jamie
* Angelique Cabral as Sarah
* Robert Patrick as Jake
* Michael Madsen as Bill
* John Rhys-Davies as Dr. Franklin
* Jim Beaver as Dr. Lewis
* Bruce Davison as Senator
* Tom Arnold as Billy
* Chris Kattan as Larry
* Krista Allen as Mrs. Lewis
* David Anders as Chad
* David Koechner as Carl
* Danika Yarosh as Kim
* Joey Lauren Adams as Mrs. Franklin
* Kevin Corrigan as Jerry
* Andrew Bowen as Scott
* Josh Pais as Jeff
This list may not be exhaustive, and could be missing some smaller roles or cameos.