Early Career (1990s):
* The Baby-Sitters Club (1995) - As Kristy Thomas
* She's All That (1999) - As Laney Boggs
* The Love Letter (1999) - As Kate McClellan
* The Virgin Suicides (1999) - As Lux Lisbon
Early 2000s:
* Get Carter (2000) - As Doreen
* Antitrust (2001) - As Lisa
* Blow Dry (2001) - As Teri
* The Banger Sisters (2002) - As Suzette
* The Whole Ten Yards (2004) - As Jill
* The Fall (2006) - As Alexandria
Later Career (2000s-2020s):
* One Last Thing (2005) - As Meredith
* The Neighbor (2007) - As Sarah
* Sherri (2007) - As Sherri
* The Perfect Age of Rock 'n' Roll (2009) - As Stella
* The Art of Getting By (2011) - As Sally
* The Chaperone (2011) - As Janet
* The Company Men (2010) - As Sally
* The Final Destination 5 (2011) - As Olivia Castle
* Psych: The Movie (2017) - As Mary Lightly
* Psych: The Movie 2 (2020) - As Mary Lightly
* The Wrong Missy (2020) - As Missy (Netflix film)
* He's All That (2021) - As Paula (Netflix film)
* WeCrashed (2022) - As Rebekah Neumann (TV series)
This is not an exhaustive list, but it covers some of her most prominent and well-known roles. Rachel Leigh Cook continues to work in film and television, showcasing her versatility as an actress.