In 1599, Shakespeare became a shareholder in the Lord Chamberlain's Men, a theatrical company. As a shareholder, he received a portion of the company's profits, which came from ticket sales and other sources. It is estimated that Shakespeare's share of these profits was around £200 per year.
In 1603, the company was renamed the King's Men and received a royal patent that granted them the exclusive right to perform plays in London. This increased their popularity and financial success, and it is likely that Shakespeare's share of the profits also increased.
Additionally, Shakespeare earned income from his playwriting. He typically sold his plays to theater companies for a one-time fee, and it is estimated that he earned around £20 to £30 per play. He also received income from the publication of his works, although this was relatively minor compared to his income from the theater.
In later years, Shakespeare also invested his money in real estate and other business ventures, which increased his wealth.
While these are just estimates, it is likely that Shakespeare's annual income during the peak of his career in the early 1600s was around £200 to £300, which would be equivalent to approximately £100,000 to £150,000 in today's money.