Plug one end of your USB cable into your M-Audio keyboard USB output. The keyboard has a mini-USB input.
Start Reason 4. Select "File," "New." A new window will open for this new project. Select "File," "Save As" to save your project.
Select "Edit," "Preferences." From the drop-down menu select "Keyboard and Control Surfaces." Select your M-Audio keyboard from the list.
Click "Miscellaneous," "Remote Control." Use this menu to map the buttons, pads or knobs on your keyboard to functions in Reason. For instance, you can use a knob to control volume or tempo. You will then be able to control parts of Reason using your keyboard.
Select "Create," "Create Instrument." Select an instrument from Reason's list, for instance a piano or guitar. Now you will be able to trigger sounds from this instrument using your M-Audio keyboard.
Select "Record" to begin recording. Play a song on your M-Audio keyboard. When you are finished select "Stop."