Plug one end of the MIDI cable into the "MIDI Out" port on your sound card or audio interface. Plug the other end into the "MIDI In 1" port on the MPC 1000.
Press the "Mode" key on the MPC 1000, then press "Pad 9" to enter the MIDI/Sync menu. Press the "F2" key. Select "1" in the "Sync In" field. Press "Main."
Double-click the Fruity Loops Studio icon on your computer to start the program. Click "Options," then "MIDI Settings." Click your sound card or MIDI interface in the "Output" list, then click and drag the "Port Number" field to select the port into which you plugged the MIDI cable.
Click the box next to "Send Master Sync" to enable it. Click the "Synchronization Type" drop-down menu and select "MIDI clock." Close the "Preferences" window. Click the "Play" button to synchronize Fruity Loops with the MPC 1000.