- The Shangri-Las
- The Shadows
- The Shaggs
- Shame
- The Shamen
- Shampoo
- Shania Twain
- Shapeshifter
- Sharon Jones & The Dap-Kings
- The Shazam
- Shawn Colvin
- Shawn Mendes
- She & Him
- Shed Seven
- Sheer Mag
- Shinedown
- The Shirelles
- Shirley Bassey
- The Shocking Blue
- Shogun
- Shook Ones
- The Showstoppers
- Shy FX
- Sia
- Sigur Rós
- Simple Minds
- Siouxsie and the Banshees
- Sister Sledge
- Sisters of Mercy
- Skids
- The Skids
- Skynyrd
- The Slackers
- Sleeper
- Sleeping with Sirens
- Sleater-Kinney
- The Sleaford Mods
- Sloan
- The Smashing Pumpkins
- The Smiths
- Smog
- The Soft Boys
- Soft Cell
- Soil & "Pimp" Sessions
- The Sounds
- The Soup Dragons
- Space
- Spacehog
- Sparks
- The Specials
- Speed of Sound
- The Spin Doctors
- The Spinners
- The Spiritualized
- The Spoons
- Spoon
- The Sports
- The Specials
- The Stone Roses
- The Stranglers
- Streetheart
- The Submarines
- Suede
- Sugababes
- Sugarcubes
- Sugarcult
- Sugar Ray
- SUM 41
- Sun Rai
- Superchunk
- Supergrass
- Supertramp
- The Swallows
- Swedish House Mafia
- Sweet
- Sweet Trip