Early Episodes & Classic Garrison:
* "Cartman Gets an Anal Probe" (Season 1, Episode 1): This episode introduces Mrs. Garrison as a straight, albeit slightly eccentric, teacher.
* "Weight Gain 4000" (Season 1, Episode 5): We see Mrs. Garrison struggling with her weight and trying various weight loss methods.
* "Volcano" (Season 1, Episode 8): The boys try to prevent an erupting volcano by using Mrs. Garrison as a sacrifice.
* "Pinkeye" (Season 1, Episode 9): Mrs. Garrison gets a strange disease that gives her the urge to eat crayons.
* "Starvin' Marvin" (Season 2, Episode 4): Mrs. Garrison takes the boys to a museum and gets them a strange souvenir.
* "Butters' Very Own Episode" (Season 2, Episode 9): Garrison becomes obsessed with a "New" student, who is actually Butters.
* "Chef Aid" (Season 3, Episode 1): Mrs. Garrison participates in the Chef Aid concert.
Garrison's Gender Transition:
* "The Passion of the Jew" (Season 18, Episode 1): The episode begins with Garrison transitioning to a man named Mr. Garrison, but later reveals that he is actually a woman who is pretending to be a man. This arc continues through the next several seasons.
* "The Hobbit" (Season 18, Episode 13): Garrison continues to grapple with his gender identity while also trying to teach his class about the "Lord of the Rings."
* "Ginger Kids" (Season 19, Episode 6): Garrison is accused of being a "ginger" and faces discrimination.
* "Gluten Free Ebola" (Season 19, Episode 1): Garrison's gender identity is challenged once again.
* "You're Not Yelping" (Season 22, Episode 10): Garrison's gender identity is explored further, and he starts to feel more comfortable in his own skin.
Garrison & Politics:
* "Ginger Kids" (Season 19, Episode 6): Garrison's political views are explored, and he becomes a vocal supporter of the "ginger" community.
* "The Magic Bush" (Season 19, Episode 10): Garrison becomes a political commentator and tries to use his influence to spread misinformation about the election.
* "The Problem with a Poo" (Season 22, Episode 9): Garrison becomes a Trump-like figure who is obsessed with poop.
Other Notable Episodes:
* "The Entity" (Season 6, Episode 10): Garrison is possessed by a mysterious entity.
* "Butters' Very Own Episode" (Season 2, Episode 9): Garrison falls in love with a "new" student who is actually Butters.
* "The Succubus" (Season 17, Episode 9): Garrison has a strange encounter with a succubus.
* "Butterballs" (Season 9, Episode 3): Garrison struggles to control his weight.
These are just a few of the many episodes that feature Mrs. Garrison. She is a complex and ever-evolving character who is always sure to provide plenty of laughs (and sometimes, controversy) on South Park.