Movies:
* Three Men and a Baby (1987)
* Three Men and a Little Lady (1990)
* So I Married an Axe Murderer (1993)
* The Last Supper (1995)
* The Kominsky Method (2018)
* The Christmas Chronicles 2 (2020)
Television:
* The Days and Nights of Molly Dodd (1987-1991) - Emmy nomination for Outstanding Lead Actress in a Comedy Series
* Almost Perfect (1995-1996)
* The Secret Life of the American Teenager (2008-2013)
* Last Man Standing (2011-2021)
* The Kominsky Method (2018-2021)
* The Afterparty (2022)
Other notable works:
* The Bob Newhart Show (1972-1978) - Guest Star
* The Golden Girls (1985-1992) - Guest Star
* Frasier (1993-2004) - Guest Star
This is not an exhaustive list, but it highlights some of her most popular and critically acclaimed work. She has also appeared in numerous other films, television series, and stage productions throughout her career.