Film:
* Blade Runner (1982): This is arguably her most famous role, playing the enigmatic replicant Rachael.
* No Way Out (1987): A political thriller where she plays a woman caught in a web of intrigue.
* Wall Street (1987): This film features her in a supporting role as a woman who becomes involved in a Wall Street insider trading scheme.
* Ace Ventura: Pet Detective (1994): She plays a quirky, albeit briefly-seen, character in this comedy.
* The Paper (1994): A drama in which she plays a strong-willed reporter.
* Striptease (1996): This film, starring Demi Moore, features her in a supporting role.
* The Man Who Knew Too Little (1997): A comedy in which she plays a CIA agent.
* The Blair Witch Project (1999): This found footage horror film features her in a brief cameo.
* The Mothman Prophecies (2002): A suspense thriller where she plays a paranormal investigator.
* The Stepfather (2009): A remake of the original film where she plays a detective.
* The Last Showing (2012): A horror film with a limited release.
* Bad Grandmas (2013): A comedy film.
* The Bounce Back (2015): A romantic comedy.
* The Christmas Chronicles 2 (2020): A Christmas-themed family film where she plays a supporting role.
Television:
* The Hitchhiker (1986-1989): She starred in several episodes of this anthology series.
* Dr. Quinn, Medicine Woman (1993-1998): She had a recurring role in this Western drama.
* Diagnosis Murder (1993-2001): She appeared in several episodes of this medical drama.
* The Outer Limits (1995-2002): She had a recurring role in this sci-fi series.
* Frasier (1993-2004): She guest-starred in a memorable episode as a love interest for Frasier Crane.
* The West Wing (2003-2006): She had a recurring role in this political drama.
* Desperate Housewives (2004-2012): She guest-starred in an episode of this popular series.
* CSI: Crime Scene Investigation (2000-2015): She appeared in an episode of this crime drama.
* Ugly Betty (2006-2010): She guest-starred in an episode of this comedy series.
* The Nanny (1993-1999): She appeared in an episode as a character called "Miss Gosh."
* The Twilight Zone (2019-present): She appeared in an episode of this revived series.
* Young Rock (2021-present): She played a fictionalized version of herself in this Dwayne Johnson comedy series.
This is just a sample of her extensive work. Her career has spanned decades, showcasing her talent in a wide range of genres.