However, the concept has been explored in various forms of media, including:
* "Jekyll & Hyde" (2015) TV series: While not featuring a female Dr. Jekyll, this series explores the character of a woman named Lily, who is deeply connected to the Jekyll and Hyde story and possesses a dark side of her own.
* "Dr. Jekyll and Ms. Hyde" (1995) comic book series: This comic book series reimagines the story with a female Dr. Jekyll and her monstrous alter ego.
* "Dr. Jekyll and Ms. Hyde" (2003) film: This movie stars Angelina Jolie as a female Dr. Jekyll, but it's not a direct adaptation of the classic story.
There have also been numerous plays and short films that have explored variations on the Jekyll and Hyde theme with female characters in the lead roles.
So, while a mainstream movie with a female Dr. Jekyll and Ms./Mrs. Hyde hasn't been made yet, the idea is certainly out there and has been explored in various forms of media. Perhaps a future movie will finally bring this intriguing concept to life!