* October Sky (1999): This drama about a young boy's dream of becoming a rocket scientist was filmed in several locations in West Virginia, including Coalwood and Beckley.
* The Mothman Prophecies (2002): This horror movie based on the real-life Mothman legend was filmed in Point Pleasant, West Virginia.
* We Are Marshall (2006): This sports drama about the Marshall University football team's recovery after a plane crash was filmed in Huntington, West Virginia.
* Shutter Island (2010): This psychological thriller set in a mental hospital was filmed in part at the former Weston State Hospital in Weston, West Virginia.
* The Cabin in the Woods (2012): This horror comedy about a group of friends who stay at a remote cabin in the woods was filmed in several locations in West Virginia, including the Monongahela National Forest.
* Wild (2014): This biographical drama about a woman's journey of self-discovery on the Pacific Crest Trail was filmed in part in West Virginia, including the Dolly Sods Wilderness.
* The Glass Castle (2017): This drama about a family's unconventional upbringing was filmed in part in Welch, West Virginia.
* Dark Waters (2019): This legal thriller about a lawyer who takes on a chemical company that is polluting a West Virginia town was filmed in part in Parkersburg, West Virginia.