Television:
* The Royle Family (1998-2012): This sitcom launched Skinner's career, she played the role of Denise Royle, the daughter of the family. She won two British Comedy Awards for her performance and the show itself was immensely popular.
* The Split (2018-present): Skinner plays the role of Hannah Defoe, one of three sisters who run a family law firm. This show was a critical success, and Skinner's performance earned her critical acclaim.
* Mum (2016-2019): Skinner played the role of Katie, in this comedy-drama series. This role earned her a BAFTA nomination.
* Doc Martin (2004-2022): Skinner had a recurring role as Louisa Glasson, a friend and confidante to the titular character.
* Benidorm (2007-2018): Skinner appeared in three episodes as a guest star.
* Goodnight Sweetheart (1993-1999): One of her early roles was as the character of "The Blonde".
* Shameless (2013-2013): Skinner appeared in one episode of the UK version of the series.
Film:
* The Boat That Rocked (2009): Skinner had a role as the character of "Ange" in this film about a pirate radio station in the 1960s.
* A Christmas Carol (2009): Skinner played the role of "Mrs Fezziwig" in this adaptation of the classic Dickens tale.
* The Wedding Video (2003): Skinner starred in this comedy film.
* The Phantom of the Opera (2004): Skinner played the role of "Madame Giry" in this film adaptation of the famous musical.
This list is not exhaustive, but it highlights some of the most prominent and successful projects Claire Skinner has been involved in. Her work has earned her critical acclaim and she continues to be a popular and respected actress in the UK.